BDBM50659756 CHEMBL6166065

SMILES C=CC(=O)Nc1ccc(Nc2nc(Nc3ccc(N4C[C@@H](C)N[C@@H](C)C4)c(OC)c3)ncc2Cl)cc1Cl

InChI Key InChIKey=PWTPVSWTQCIBGE-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50659756   

TargetFibroblast growth factor receptor 2(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659756BDBM50659756(CHEMBL6166065)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of FGFR2 V564F mutant (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659756BDBM50659756(CHEMBL6166065)
Affinity DataIC50: 2nMAssay Description:Inhibition of FGFR1 V561M mutant (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetFibroblast growth factor receptor 3(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659756BDBM50659756(CHEMBL6166065)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of FGFR3 V555L mutant (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetFibroblast growth factor receptor 3(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659756BDBM50659756(CHEMBL6166065)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of FGFR3 V555M mutant (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659756BDBM50659756(CHEMBL6166065)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of wild type FGFR1 (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetFibroblast growth factor receptor 2(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659756BDBM50659756(CHEMBL6166065)
Affinity DataIC50: 16nMAssay Description:Inhibition of wild type FGFR2 (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetFibroblast growth factor receptor 3(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659756BDBM50659756(CHEMBL6166065)
Affinity DataIC50: 19nMAssay Description:Inhibition of wild type FGFR3 (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetFibroblast growth factor receptor 2(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659756BDBM50659756(CHEMBL6166065)
Affinity DataIC50: 30nMAssay Description:Inhibition of FGFR2 V564I mutant (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetFibroblast growth factor receptor 4(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659756BDBM50659756(CHEMBL6166065)
Affinity DataIC50: 486nMAssay Description:Inhibition of wild type FGFR4 (unknown origin) by caliper mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed