BDBM50659808 CHEMBL6148332

SMILES Cc1cc(NC(=O)C(=O)N2C[C@@H](C)N(C)C[C@@H]2c2ccc(F)cc2)cnc1N

InChI Key InChIKey=BKDVOCGDHAHKGZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50659808   

TargetProtein arginine N-methyltransferase 5(Human)
Tango Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659808BDBM50659808(CHEMBL6148332)
Affinity DataIC50: 25nMAssay Description:Inhibition of PRMT5 in MTAP-null human HAP1 cells assessed as decrease in SDMA level incubated for 24 hrs by ICW assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed