BDBM50659823 CHEMBL6167512

SMILES CC(C)C(=O)N1C[C@H](c2ccc3scnc3c2)N(C(=O)C(=O)Nc2cnc(N)c3cn[nH]c23)C[C@H]1C

InChI Key InChIKey=GCTCIWYVFGFHMF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50659823   

TargetProtein arginine N-methyltransferase 5(Human)
Tango Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50659823BDBM50659823(CHEMBL6167512)
Affinity DataIC50: 16nMAssay Description:Inhibition of PRMT5 in MTAP-null human HAP1 cells assessed as decrease in SDMA level incubated for 24 hrs by ICW assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed