BDBM50660022 CHEMBL6162052

SMILES CSc1ccccc1[C@H]1CCCN1C(=O)CNC(=O)N(Cc1ccc2c(c1)[C@@]1(C)C[C@@](C)(N2)[C@H](O)CO1)Cc1nnn(C)n1

InChI Key InChIKey=ZSFCSVBUTUAFEQ-UHFFFAOYSA-N

Data  2 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50660022   

TargetPeptidyl-prolyl cis-trans isomerase A(Human)
University of Edinburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660022BDBM50660022(CHEMBL6162052)
Affinity DataKd:  6nMAssay Description:Binding affinity to human full length N-terminal CypA (1 to 165 residues) extracted from Escherichia coli BL21 (DE3) cells assessed as dissociation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetPeptidyl-prolyl cis-trans isomerase F, mitochondrial(Human)
University of Edinburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660022BDBM50660022(CHEMBL6162052)
Affinity DataKd:  8nMAssay Description:Binding affinity to human full length N-terminal CypD (42 to 207 residues) extracted from Escherichia coli BL21 (DE3) cells assessed as dissociation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetPeptidyl-prolyl cis-trans isomerase F, mitochondrial(Human)
University of Edinburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660022BDBM50660022(CHEMBL6162052)
Affinity DataEC50:  244nMAssay Description:Inhibition of CypD mediated opening to mitochondrial transition pore in human HepG2 cells by FLIPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed