BDBM50660961 CHEMBL6174967

SMILES N=C(N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(N)=O)NC(=O)OCc1ccccc1)C(=O)c1nccs1

InChI Key InChIKey=YULXMMYEJYZEGC-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50660961   

TargetTransmembrane protease serine 2(Human)
University of Sherbrooke

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660961BDBM50660961(CHEMBL6174967)
Affinity DataKi:  0.0300nMAssay Description:Inhibition of recombinant das TMPRSS2 (unknown origin) extracted from baculovirus infected in Sf9 cells assessed as inhibition constant using Boc-QAR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTransmembrane protease serine 2(Human)
University of Sherbrooke

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660961BDBM50660961(CHEMBL6174967)
Affinity DataIC50: 0.350nMAssay Description:Inhibition of recombinant TMPRSS2 (unknown origin) extracted from baculovirus infected in Sf9 cells using Boc-QAR-AMC as substrate measured after 1 h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTransmembrane protease serine 2(Human)
University of Sherbrooke

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660961BDBM50660961(CHEMBL6174967)
Affinity DataIC50: 0.590nMAssay Description:Inhibition of full length TMPRSS2 (unknown origin) expressed in African green monkey Vero E6 cells using Boc-QAR-AMC as substrate incubated for 24 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTransmembrane protease serine 2(Human)
University of Sherbrooke

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660961BDBM50660961(CHEMBL6174967)
Affinity DataKi:  12nMAssay Description:Inhibition of TMPRSS2 (unknown origin) assessed as inhibition constant using Boc-RRVR-AMC as substrate incubated for 1 hr by fluorescence based analy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed