BDBM50662028 CHEMBL71728

SMILES Cc1cc(c(c(c1)C)Nc2ncnc(n2)Nc3ccc(cc3)C#N)C

InChI Key InChIKey=SOPKWXMQSHLEKD-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50662028   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662028BDBM50662028(CHEMBL71728)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of wild type HIV-1 LAI reverse transcriptaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662028BDBM50662028(CHEMBL71728)
Affinity DataIC50: 3nMAssay Description:Inhibition of HIV-1 Reverse transcriptase K103N mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662028BDBM50662028(CHEMBL71728)
Affinity DataIC50: 50nMAssay Description:Inhibition of HIV-1 Reverse transcriptase K103N/Y181C double mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sapienza University of Rome

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662028BDBM50662028(CHEMBL71728)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of HIV-1 Reverse transcriptase L100I/K103N double mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)