BDBM50662071 CHEMBL6175124

SMILES CN1CCN(Cc2ccc(-c3cn([C@H]4CC[C@H](O)CC4)c4nc(Nc5cc(C(F)(F)F)cc(C(F)(F)F)c5)ncc34)cc2)CC1

InChI Key InChIKey=CPWDPNAAVHWMCG-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50662071   

TargetTyrosine-protein kinase receptor TYRO3(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662071BDBM50662071(CHEMBL6175124)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of TYRO3 (unknown origin) by microcapillary electrophoresis (MCE) assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein kinase receptor TYRO3(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662071BDBM50662071(CHEMBL6175124)
Affinity DataEC50:  90nMAssay Description:Inhibition of TYRO3 (unknown origin) expressed in HEK293 cells assessed as cellular target engagement measured after 1 hr incubation by NanoBRET intr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662071BDBM50662071(CHEMBL6175124)
Affinity DataIC50: 190nMAssay Description:Inhibition of AXL (unknown origin) by microcapillary electrophoresis (MCE) assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein kinase Mer(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662071BDBM50662071(CHEMBL6175124)
Affinity DataIC50: 580nMAssay Description:Inhibition of MERTK (unknown origin) by microcapillary electrophoresis (MCE) assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662071BDBM50662071(CHEMBL6175124)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of AXL (unknown origin) expressed in HEK293 cells assessed as cellular target engagement measured after 1 hr incubation by NanoBRET intrac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed