BDBM50662778 CHEMBL6175324

SMILES C[C@@]1(CO)CN=C(Nc2cc(F)c(Oc3ccnc4[nH]cc(C5(C(F)F)CC5)c34)c(F)c2)OC1

InChI Key InChIKey=SOSSJZICJXFJJF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50662778   

LigandChemical structure of BindingDB Monomer ID 50662778BDBM50662778(CHEMBL6175324)
Affinity DataIC50: 2nMAssay Description:Displacement of Tracer222 from N-terminal GST-tagged/TEV-fused human full length wild type MAP4K1 expressed in baculovirus-infected Sf9 cells incubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50662778BDBM50662778(CHEMBL6175324)
Affinity DataIC50: 210nMAssay Description:Inhibition of MAP4K1 in human Jurkat E6.1 cells expressing FLAG-tagged human SLP76 assessed as inhibition of SLP76 phosphorylation at Ser376 residue ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed