BDBM50663325 CHEMBL6164852

SMILES COc1cc(NC2=NC(=O)C3(CCc4ncccc43)c3cc(C(F)(F)F)ccc32)ccn1

InChI Key InChIKey=YVNDZMAGSOMOTL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50663325   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Shanghai Haiyan Pharmaceutical Technology Co., Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663325BDBM50663325(CHEMBL6164852)
Affinity DataIC50: 12nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine pre-incubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed