BDBM50663485 CHEMBL6161072

SMILES C[C@@H](n1cc(-c2cncc(N(C)C)c2)nn1)n1ccc(N2CCC[C@@H](NCC3CC3)C2)cc1=O

InChI Key InChIKey=SIMGHJKPZKGPGZ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50663485   

LigandChemical structure of BindingDB Monomer ID 50663485BDBM50663485(CHEMBL6161072)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]-SAM from METTL3/METTL14 (unknown origin) using 5'biotinylated-UACACUCGAUCUGGACUAAAGGUGCUC-3' RNA as substrate preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50663485BDBM50663485(CHEMBL6161072)
Affinity DataIC50: 3nMAssay Description:Inhibition of METTL3/METTL14-mediated m6A mRNA expression in human SK-OV-3 cells incubated for 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50663485BDBM50663485(CHEMBL6161072)
Affinity DataIC50: 5nMAssay Description:Inhibition of METTL3/METTL14-mediated m6A mRNA expression in human MV4-11 cells incubated for 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50663485BDBM50663485(CHEMBL6161072)
Affinity DataIC50: 5nMAssay Description:Inhibition of METTL3/METTL14-mediated m6A mRNA expression in human Kasumi 1 cells incubated for 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50663485BDBM50663485(CHEMBL6161072)
Affinity DataIC50: 6nMAssay Description:Inhibition of METTL3/METTL14-mediated m6A mRNA expression in human FaDu cells incubated for 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50663485BDBM50663485(CHEMBL6161072)
Affinity DataIC50: 7nMAssay Description:Inhibition of METTL3/METTL14-mediated m6A mRNA expression in human A549 cells incubated for 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50663485BDBM50663485(CHEMBL6161072)
Affinity DataIC50: 9nMAssay Description:Inhibition of METTL3/METTL14-mediated m6A mRNA expression in human Calu-6 cells incubated for 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed