BDBM50664964 CHEMBL6176850

SMILES Nc1cc(-c2ccc3c(c2)CC(=O)N(c2ccccc2)CC3)ccn1

InChI Key InChIKey=GPXQQRVBMWXGOC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50664964   

TargetRho-associated protein kinase 2(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664964BDBM50664964(CHEMBL6176850)
Affinity DataKi:  16nMAssay Description:Inhibition of N-terminal-His6-tagged_ZB_TEV fused ROCK2 catalytic domain (19 to 417 residues) (unknown origin) expressed in insect High Five cells as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
Chiesi Farmaceutici S.p.A

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664964BDBM50664964(CHEMBL6176850)
Affinity DataKi:  50nMAssay Description:Inhibition of human ROCK1 assessed as inhibition constant in presence of ATP at >>Km concentrationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed