BDBM50665227 CHEMBL6152177

SMILES N[C@H]1CC[C@@H](N2CCCCCN3/C(=N/S(=O)(=O)c4cnc(N5CCNCC5)c(c4)C2=O)Sc2c(Cl)ccc(O)c23)CC1

InChI Key InChIKey=HYXFXJLSWLESFO-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50665227   

TargetGTPase KRas(Human)
CRUK Scotland Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665227BDBM50665227(CHEMBL6152177)
Affinity DataKd:  160nMAssay Description:Binding affinity to GDP-bound KRAS G12D mutant (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetGTPase KRas(Human)
CRUK Scotland Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665227BDBM50665227(CHEMBL6152177)
Affinity DataKd:  1.41E+3nMAssay Description:Binding affinity to GMPPNP-bound KRAS G12D mutant (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed