BDBM50665440 CHEMBL6169035

SMILES CCNNC(=O)c1cc(F)c(CN2c3ccccc3C=Cc3ccncc32)cc1F

InChI Key InChIKey=PHUYQMKFLKAVAP-UHFFFAOYSA-N

Data  17 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50665440   

TargetHistone deacetylase 6(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665440BDBM50665440(CHEMBL6169035)
Affinity DataIC50: 17.2nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using Boc-Lys (acetyl)-AMC as substrate preincubated for 120 mins followed by substrate addition and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665440BDBM50665440(CHEMBL6169035)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant full-length human HDAC6 using Boc-Lys (acetyl)-AMC as substrate preincubated for 1 hrs followed by substrate addition and m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665440BDBM50665440(CHEMBL6169035)
Affinity DataIC50: 32.4nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using Boc-Lys (acetyl)-AMC as substrate preincubated for 60 mins followed by substrate addition and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665440BDBM50665440(CHEMBL6169035)
Affinity DataIC50: 141nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using Boc-Lys (acetyl)-AMC as substrate preincubated for 90 mins followed by substrate addition and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665440BDBM50665440(CHEMBL6169035)
Affinity DataIC50: 163nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using Boc-Lys (acetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665440BDBM50665440(CHEMBL6169035)
Affinity DataIC50: 207nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using Boc-Lys (acetyl)-AMC as substrate preincubated for 15 mins followed by substrate addition and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665440BDBM50665440(CHEMBL6169035)
Affinity DataIC50: 427nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using Boc-Lys (acetyl)-AMC as substrate incubated for 2 hrs by fluorescence based plate reader analy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665440BDBM50665440(CHEMBL6169035)
Affinity DataIC50: 7.04E+3nMAssay Description:Inhibition of recombinant HDAC3 (unknown origin) using Boc-Lys (acetyl)-AMC as substrate preincubated for 1 hrs followed by substrate addition and me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665440BDBM50665440(CHEMBL6169035)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant HDAC8 (unknown origin) using Boc-Lys (trifluoroacetyl)AMC as substrate preincubated for 1 hrs followed by substrate additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 9(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665440BDBM50665440(CHEMBL6169035)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant HDAC9 (unknown origin) using Boc-Lys (trifluoroacetyl)AMC as substrate preincubated for 1 hrs followed by substrate additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665440BDBM50665440(CHEMBL6169035)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant HDAC5 (unknown origin) using Boc-Lys (trifluoroacetyl)AMC as substrate preincubated for 1 hrs followed by substrate additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665440BDBM50665440(CHEMBL6169035)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant HDAC7 (unknown origin) using Boc-Lys (trifluoroacetyl)AMC as substrate preincubated for 1 hrs followed by substrate additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665440BDBM50665440(CHEMBL6169035)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant HDAC4 (unknown origin) using Boc-Lys (trifluoroacetyl)AMC as substrate preincubated for 1 hrs followed by substrate additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665440BDBM50665440(CHEMBL6169035)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using Boc-Lys (acetyl)-AMC as substrate preincubated for 1 hrs followed by substrate addition and me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665440BDBM50665440(CHEMBL6169035)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant HDAC10 (unknown origin) using Ac-Gly-Ala-Lys(AMC) as substrate preincubated for 1 hrs followed by substrate addition and me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665440BDBM50665440(CHEMBL6169035)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant HDAC11 (unknown origin) using ETDKacyl-Kmyr as substrate preincubated for 1 hrs followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Ocean University of China

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665440BDBM50665440(CHEMBL6169035)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant HDAC2 (unknown origin) using Boc-Lys (acetyl)-AMC as substrate preincubated for 1 hrs followed by substrate addition and me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed