BDBM50665506 CHEMBL6159776

SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(C#Cc3ccc(OCCCN4CCOCC4)cc3)cc2)no1

InChI Key InChIKey=DWZXYPARIPYQKS-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50665506   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Sunshine Lake Pharma Company, Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665506BDBM50665506(CHEMBL6159776)
Affinity DataIC50: 15nMAssay Description:Inhibition of human FLT3 ITD mutant by biochemical kinase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Sunshine Lake Pharma Company, Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665506BDBM50665506(CHEMBL6159776)
Affinity DataIC50: 25nMAssay Description:Inhibition of human FLT3 by biochemical kinase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Sunshine Lake Pharma Company, Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665506BDBM50665506(CHEMBL6159776)
Affinity DataIC50: 63nMAssay Description:Inhibition of human PDGFRA V561D mutant by biochemical kinase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Sunshine Lake Pharma Company, Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665506BDBM50665506(CHEMBL6159776)
Affinity DataIC50: 110nMAssay Description:Inhibition of human RET by biochemical kinase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Sunshine Lake Pharma Company, Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665506BDBM50665506(CHEMBL6159776)
Affinity DataIC50: 119nMAssay Description:Inhibition of human RET Y791F mutant by biochemical kinase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Sunshine Lake Pharma Company, Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665506BDBM50665506(CHEMBL6159776)
Affinity DataIC50: 133nMAssay Description:Inhibition of human CSF1R by biochemical kinase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Sunshine Lake Pharma Company, Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665506BDBM50665506(CHEMBL6159776)
Affinity DataIC50: 139nMAssay Description:Inhibition of human PDGFR alpha by biochemical kinase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Sunshine Lake Pharma Company, Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665506BDBM50665506(CHEMBL6159776)
Affinity DataIC50: 283nMAssay Description:Inhibition of human KIT V559D/T670I mutant by biochemical kinase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Sunshine Lake Pharma Company, Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665506BDBM50665506(CHEMBL6159776)
Affinity DataIC50: 283nMAssay Description:Inhibition of human KIT Y823D mutant by biochemical kinase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Sunshine Lake Pharma Company, Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665506BDBM50665506(CHEMBL6159776)
Affinity DataIC50: 422nMAssay Description:Inhibition of human DDR2 T654M mutant by biochemical kinase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Sunshine Lake Pharma Company, Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665506BDBM50665506(CHEMBL6159776)
Affinity DataIC50: 439nMAssay Description:Inhibition of human RET G691S mutant by biochemical kinase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Sunshine Lake Pharma Company, Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665506BDBM50665506(CHEMBL6159776)
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of human PDGFR beta by biochemical kinase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Sunshine Lake Pharma Company, Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665506BDBM50665506(CHEMBL6159776)
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of human KIT by biochemical kinase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed