BDBM50665671 CHEMBL6151656

SMILES O=C(Nc1ccc(Oc2ccccc2)c(Cl)c1)C(=O)NC1CCCCC1NC(=O)[C@H](c1ccccc1)S(=O)(=O)O

InChI Key InChIKey=JEHSWMKPHPDWMO-UHFFFAOYSA-N

Data  1 KI  19 IC50  1 Kd

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 50665671   

TargetLaforin(Human)
Purdue University

Curated by ChEMBL

LigandBDBM50665671(CHEMBL6151656)Copy SMILESCopy InChI

Affinity DataKi:  1.90nMAssay Description:Competitive inhibition of His-tagged laforin (unknown origin) extracted from Escherichia coli BL21 using pNPP as substrate assessed a inhibition cons...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
6/6/2026
Entry Details
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TargetLaforin(Human)
Purdue University

Curated by ChEMBL

LigandBDBM50665671(CHEMBL6151656)Copy SMILESCopy InChI

Affinity DataKd:  2.10nMAssay Description:Binding affinity to laforin (unknown origin) assessed as dissociation constant by MST analysisMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
6/6/2026
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TargetLaforin(Human)
Purdue University

Curated by ChEMBL

LigandBDBM50665671(CHEMBL6151656)Copy SMILESCopy InChI

Affinity DataIC50: 2.5nMAssay Description:Inhibition of His-tagged laforin (unknown origin) extracted from Escherichia coli BL21 using pNPP as substrate assessed as substrate hydrolysis incub...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
6/6/2026
Entry Details
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TargetLaforin(Human)
Purdue University

Curated by ChEMBL

LigandBDBM50665671(CHEMBL6151656)Copy SMILESCopy InChI

Affinity DataIC50: 3.90nMAssay Description:Inhibition of His-tagged laforin (unknown origin) extracted from Escherichia coli BL21 using pNPP as substrate assessed as substrate hydrolysis incub...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
6/6/2026
Entry Details
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TargetLaforin(Human)
Purdue University

Curated by ChEMBL

LigandBDBM50665671(CHEMBL6151656)Copy SMILESCopy InChI

Affinity DataIC50: 4nMAssay Description:Inhibition of His-tagged laforin (unknown origin) extracted from Escherichia coli BL21 using pNPP as substrate assessed as substrate hydrolysis incub...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
6/6/2026
Entry Details
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TargetLaforin(Human)
Purdue University

Curated by ChEMBL

LigandBDBM50665671(CHEMBL6151656)Copy SMILESCopy InChI

Affinity DataIC50: 7.70nMAssay Description:Inhibition of His-tagged laforin (unknown origin) extracted from Escherichia coli BL21 using pNPP as substrate assessed as substrate hydrolysis incub...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
6/6/2026
Entry Details
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TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Purdue University

Curated by ChEMBL

LigandBDBM50665671(CHEMBL6151656)Copy SMILESCopy InChI

Affinity DataIC50: 3.32E+4nMAssay Description:Inhibition of His-tagged SHP2 (unknown origin) extracted from Escherichia coli BL21 using pNPP as substrate incubated for 80 mins by spectrophotometr...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
6/6/2026
Entry Details
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TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Purdue University

Curated by ChEMBL

LigandBDBM50665671(CHEMBL6151656)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of His-tagged TC-PTP (unknown origin) extracted from Escherichia coli BL21 using pNPP as substrate incubated for 80 mins by spectrophotome...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
6/6/2026
Entry Details
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TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Purdue University

Curated by ChEMBL

LigandBDBM50665671(CHEMBL6151656)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of His-tagged PTP-alpha (unknown origin) extracted from Escherichia coli BL21 using pNPP as substrate incubated for 80 mins by spectrophot...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
6/6/2026
Entry Details
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TargetTyrosine-protein phosphatase non-receptor type 7(Human)
Purdue University

Curated by ChEMBL

LigandBDBM50665671(CHEMBL6151656)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of His-tagged HePTP (unknown origin) extracted from Escherichia coli BL21 using pNPP as substrate incubated for 80 mins by spectrophotomet...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
6/6/2026
Entry Details
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TargetTyrosine-protein phosphatase non-receptor type 5(Human)
Purdue University

Curated by ChEMBL

LigandBDBM50665671(CHEMBL6151656)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of His-tagged STEP (unknown origin) extracted from Escherichia coli BL21 using pNPP as substrate incubated for 80 mins by spectrophotometr...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
6/6/2026
Entry Details
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TargetReceptor-type tyrosine-protein phosphatase C(Human)
Purdue University

Curated by ChEMBL

LigandBDBM50665671(CHEMBL6151656)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of His-tagged CD45 (unknown origin) extracted from Escherichia coli BL21 using pNPP as substrate incubated for 80 mins by spectrophotometr...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
6/6/2026
Entry Details
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TargetDual specificity protein phosphatase 3(Human)
Purdue University

Curated by ChEMBL

LigandBDBM50665671(CHEMBL6151656)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of His-tagged VHR (unknown origin) extracted from Escherichia coli BL21 using pNPP as substrate incubated for 80 mins by spectrophotometri...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
6/6/2026
Entry Details
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TargetReceptor-type tyrosine-protein phosphatase beta(Human)
Purdue University

Curated by ChEMBL

LigandBDBM50665671(CHEMBL6151656)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of His-tagged PTP-beta (unknown origin) extracted from Escherichia coli BL21 using pNPP as substrate incubated for 80 mins by spectrophoto...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
6/6/2026
Entry Details
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TargetReceptor-type tyrosine-protein phosphatase F(Human)
Purdue University

Curated by ChEMBL

LigandBDBM50665671(CHEMBL6151656)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of His-tagged LAR (unknown origin) extracted from Escherichia coli BL21 using pNPP as substrate incubated for 80 mins by spectrophotometri...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
6/6/2026
Entry Details
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TargetLow molecular weight phosphotyrosine protein phosphatase(Human)
Purdue University

Curated by ChEMBL

LigandBDBM50665671(CHEMBL6151656)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of His-tagged LMW-PTP (unknown origin) extracted from Escherichia coli BL21 using pNPP as substrate incubated for 80 mins by spectrophotom...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
6/6/2026
Entry Details
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TargetReceptor-type tyrosine-protein phosphatase delta(Homo sapiens)
Purdue University

Curated by ChEMBL

LigandBDBM50665671(CHEMBL6151656)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of His-tagged PTP-delta (unknown origin) extracted from Escherichia coli BL21 using pNPP as substrate incubated for 80 mins by spectrophot...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
6/6/2026
Entry Details
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TargetProtein-tyrosine-phosphatase(Yersinia pestis)
Purdue University

Curated by ChEMBL

LigandBDBM50665671(CHEMBL6151656)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of His-tagged Yersinia pseudotuberculosis IP32953 YopH extracted from Escherichia coli BL21 using pNPP as substrate incubated for 80 mins ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
6/6/2026
Entry Details
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TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Purdue University

Curated by ChEMBL

LigandBDBM50665671(CHEMBL6151656)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of His-tagged PTP1B (unknown origin) extracted from Escherichia coli BL21 using pNPP as substrate incubated for 80 mins by spectrophotomet...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
6/6/2026
Entry Details
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TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Purdue University

Curated by ChEMBL

LigandBDBM50665671(CHEMBL6151656)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of His-tagged LYP (unknown origin) extracted from Escherichia coli BL21 using pNPP as substrate incubated for 80 mins by spectrophotometri...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
6/6/2026
Entry Details
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TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Purdue University

Curated by ChEMBL

LigandBDBM50665671(CHEMBL6151656)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of His-tagged SHP1 (unknown origin) extracted from Escherichia coli BL21 using pNPP as substrate incubated for 80 mins by spectrophotometr...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
6/6/2026
Entry Details
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