BDBM50665838 CHEMBL6177652

SMILES O=C(NO)c1cc(F)c(CN2CN(c3ccccc3)C3(CCN(Cc4ccccc4)CC3)C2=O)c(F)c1

InChI Key InChIKey=ZDMMFCDOFCJQAV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50665838   

TargetHistone deacetylase 6(Human)
University of Naples Federico II

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665838BDBM50665838(CHEMBL6177652)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of N-terminal GST-tagged human full length recombinant HDAC6 (1 to 1215 residues) expressed in Sf9 insect cells using Fluor-de-Lys green a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
University of Naples Federico II

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665838BDBM50665838(CHEMBL6177652)
Affinity DataIC50: 3.26E+3nMAssay Description:Inhibition of C-terminal His-tagged full length human recombinant HDAC8 (1 to 377 residues) expressed in Sf9 cells using Fluor-de-Lys green as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
University of Naples Federico II

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665838BDBM50665838(CHEMBL6177652)
Affinity DataIC50: 7.38E+3nMAssay Description:Inhibition of C-terminal 6XHis-tagged/FLAG-tagged full length human recombinant HDAC1 (1 to 482 residues) expressed in Sf9 cells using Fluor-de-Lys g...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed