BDBM50665871 CHEMBL6168427

SMILES O=C(NCCCc1cccnc1)Nc1ccc(S(=O)(=O)N(Cc2ccc(Cl)cc2)C2CCCC2)cc1

InChI Key InChIKey=PYIJMHVSGSHTMZ-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50665871   

LigandChemical structure of BindingDB Monomer ID 50665871BDBM50665871(CHEMBL6168427)
Affinity DataKd:  0.670nMAssay Description:Binding affinity to PDEdelta (unknown origin) assessed as binding inhibition constant (Kd) incubated for 10 hrs in presence of atorvastatin-FITC prob...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665871BDBM50665871(CHEMBL6168427)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of NAMPT (unknown origin) using NAM as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed