BDBM50665877 CHEMBL6175400

SMILES COc1ccc(CN(C2CCCC2)S(=O)(=O)c2ccc(NC(=O)NCc3cccnc3)cc2)cc1

InChI Key InChIKey=PUYQBFOBGRNWMC-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50665877   

LigandChemical structure of BindingDB Monomer ID 50665877BDBM50665877(CHEMBL6175400)
Affinity DataKd:  0.410nMAssay Description:Binding affinity to PDEdelta (unknown origin) assessed as binding inhibition constant (Kd) incubated for 10 hrs in presence of atorvastatin-FITC prob...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Shanghai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665877BDBM50665877(CHEMBL6175400)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of NAMPT (unknown origin) using NAM as substrate preincubated for 5 mins followed by substrate addition and measured after 15 mins by fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed