BDBM50666684 CHEMBL6177744

SMILES Cn1c(ccn1)Cc2ccc3c(c2)CCN(C3)[C@@H]4CCN(C[C@H]4O)C(=O)c5ccnc(c5)NC6CCC6

InChI Key InChIKey=KQBRZVZHHHSTLW-UHFFFAOYSA-N

Data  2 KI

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50666684   

LigandChemical structure of BindingDB Monomer ID 50666684BDBM50666684(CHEMBL6177744)
Affinity DataKi:  200nMAssay Description:Inhibition of PRMT5/MEP50 (unknown origin) using TAMRA-labeled histone H4 peptide as substrate in presence of MTA by fluorescence anisotropy peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50666684BDBM50666684(CHEMBL6177744)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of PRMT5/MEP50 (unknown origin) using TAMRA-labeled histone H4 peptide as substrate in presence of SAM by fluorescence anisotropy peptide ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)