BDBM50666711 CHEMBL6177605

SMILES C=CC(=O)N1CC2(CCN(c3nc(N[C@H](CC(=O)NC)CC(C)C)nc(-c4cccc(OC)c4Cl)n3)CC2)C1

InChI Key InChIKey=DEDZMTLXTZRZKB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50666711   

TargetGTPase KRas(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666711BDBM50666711(CHEMBL6177605)
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of recombinant His-tagged GDP-bound human KRAS G12C/C118A mutant (1 to 169 residues) (unknown origin) extracted by Escherichia coli assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed