BDBM50666716 CHEMBL6176399

SMILES C=CC(=O)N1CC2(CCN(c3nc4c(c(-c5c(C)ccc6[nH]ncc56)n3)CCC(C)(C)C4)C2)C1

InChI Key InChIKey=LKUSNJFZJXECCP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50666716   

TargetGTPase KRas(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666716BDBM50666716(CHEMBL6176399)
Affinity DataIC50: 840nMAssay Description:Inhibition of recombinant His-tagged GDP-bound human KRAS G12C/C118A mutant (1 to 169 residues) (unknown origin) extracted by Escherichia coli assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed