BDBM50667689 CHEMBL6188771

SMILES COc1cc(N2CCN(C)CC2)ccc1-n1cnc(Nc2cnc(C#N)cn2)c1

InChI Key InChIKey=REUDKWLNHJXUHV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50667689   

TargetSerine/threonine-protein kinase Chk1(Human)
BenevolentAI

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667689BDBM50667689(CHEMBL6188771)
Affinity DataIC50: 10nMAssay Description:Inhibition of N-terminal GST-fused human full length CHK1 (1 to 476 residues) expressed in baculovirus-infected Sf21 cells using STK1 S1 as substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
BenevolentAI

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667689BDBM50667689(CHEMBL6188771)
Affinity DataIC50: 8.83E+3nMAssay Description:Inhibition of N-terminal GST-fused human full length CHK2 (1 to 543 residues) expressed in baculovirus-infected Sf21 cells using STK1 S1 as substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed