BDBM50667875 CHEMBL6189181

SMILES O=C(c1ccc(F)c(F)c1)N1CCC(c2cc(-c3ccnc4[nH]ccc34)[nH]n2)CC1

InChI Key InChIKey=IRNPWSDNANXVSS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50667875   

TargetRho-associated protein kinase 1(Human)
Shandong First Medical University & Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667875BDBM50667875(CHEMBL6189181)
Affinity DataIC50: 699nMAssay Description:Inhibition of ROCK1 (unknown origin) incubated for 40 mins in presence of ATP by ADP-glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Shandong First Medical University & Shandong Academy of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667875BDBM50667875(CHEMBL6189181)
Affinity DataIC50: 907nMAssay Description:Inhibition of ROCK2 (unknown origin) incubated for 40 mins in presence of ATP by ADP-glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed