BDBM506679 N-(5-bromopyrazin-2-yl)-2- ((1R,3s,5S,6r)-3-(5,6- difluoro-1H-benzo[d]- imidazol-1-yl)bicyclo- [3.1.0]hexan-6-yl)- propanamide::US11046649, Ex. 57

SMILES CC([C@@H]1[C@H]2C[C@@H](C[C@@H]12)n1cnc2cc(F)c(F)cc12)C(=O)Nc1cnc(Br)cn1

InChI Key InChIKey=SMNIZLBXAVDRIQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 506679   

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandPNGBDBM506679(US11046649, Ex. 57 | N-(5-bromopyrazin-2-yl)-2- ((...)
Affinity DataIC50: 2.40nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent