BDBM50667951 CHEMBL6189997

SMILES C[C@H](Nc1nc(Nc2cnn(CC(F)(F)F)c2)nc2[nH]ccc12)C1CC1

InChI Key InChIKey=SWCSKMXOAOVQNC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50667951   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Duke University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667951BDBM50667951(CHEMBL6189997)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant wild type GST-LRRK2 (unknown origin) purified from baculovirus infected Sf9 cells assessed as autophosphorylation using RLG...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Duke University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667951BDBM50667951(CHEMBL6189997)
Affinity DataIC50: 10nMAssay Description:Inhibition of LRRK2 G2019S mutant (unknown origin) purified from baculovirus infected Sf9 cells assessed as autophosphorylation using RLGAWRFYTLRRARQ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed