BDBM50668137 CHEMBL6193682

SMILES CC(C)Oc1cc(F)ccc1-c1ccnc(NC(=O)Nc2cccc(C(=O)N3CCN(C)CC3)c2)c1

InChI Key InChIKey=GSLHDZCTAHKMDW-UHFFFAOYSA-N

Data  5 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50668137   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668137BDBM50668137(CHEMBL6193682)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of His-tagged full length human recombinant CDK9/cyclinT1 using KTFCGTPEYLAPEVRREPRILSEEEQEMFRDFDYIADWC as substrate incubated for 60 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668137BDBM50668137(CHEMBL6193682)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of CDK2/cyclA2 (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668137BDBM50668137(CHEMBL6193682)
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of CDK4/cycD3 (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668137BDBM50668137(CHEMBL6193682)
Affinity DataIC50: 3.87E+3nMAssay Description:Inhibition of CDK1/cyclA2 (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668137BDBM50668137(CHEMBL6193682)
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of CDK6/cycD3 (unknown origin) by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668137BDBM50668137(CHEMBL6193682)
Affinity DataKd:  8.87E+3nMAssay Description:Binding affinity to CDK9/cyclin T1 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed