BDBM506732 2-cyclopropyl-N-(6-cyclo- propylpyridin-3-yl)-2- ((1R,3s,5S,6r)-3-((6- fluoroquinolin-4-yl)oxy)- bicyclo[3.1.0]hexan-6-yl)- acetamide::US11046649, Ex. 110

SMILES Fc1ccc2nccc(O[C@H]3C[C@H]4[C@@H](C3)[C@@H]4C(C3CC3)C(=O)Nc3ccc(nc3)C3CC3)c2c1

InChI Key InChIKey=CENYRCJJTSNZJT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 506732   

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandPNGBDBM506732(US11046649, Ex. 110 | 2-cyclopropyl-N-(6-cyclo- pr...)
Affinity DataIC50: 1.82nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent