BDBM506745 2-cyclopropyl-2- ((1R,3s,5S,6r)-3-((6- fluoroquinolin-4-yl)oxy)- bicyclo[3.1.0]hexan-6-yl)- N-(5-methylpyrazin-2-yl)- acetamide::US11046649, Ex. 123

SMILES Cc1cnc(NC(=O)C(C2CC2)[C@@H]2[C@H]3C[C@@H](C[C@@H]23)Oc2ccnc3ccc(F)cc23)cn1

InChI Key InChIKey=NBHALIAIOLDNNY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 506745   

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandPNGBDBM506745(2-cyclopropyl-2- ((1R,3s,5S,6r)-3-((6- fluoroquino...)
Affinity DataIC50: 1.54nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent