BDBM506748 2-cyclopropyl-N-(1- (difluoromethyl)-1H- pyrazol-4-yl)-2- ((1R,3s,5S,6r)-3-((6- fluoroquinolin-4-yl)oxy)- bicyclo[3.1.0]hexan-6- yl)acetamide::US11046649, Ex. 126

SMILES FC(F)n1cc(NC(=O)C(C2CC2)[C@@H]2[C@H]3C[C@@H](C[C@@H]23)Oc2ccnc3ccc(F)cc23)cn1

InChI Key InChIKey=LABLGMZRWOQSIG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 506748   

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Of Texas

US Patent
LigandPNGBDBM506748(2-cyclopropyl-N-(1- (difluoromethyl)-1H- pyrazol-4...)
Affinity DataIC50: 2.85nMAssay Description:HeLa cells were obtained from the American Type Culture Collection (ATCC) and maintained in DMEM media containing 10% FBS. Cells (7,000/well) were se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent