BDBM50679 (5Z)-5-(2-furanylmethylidene)-3-(3-pyridinyl)-2-sulfanylidene-4-thiazolidinone::(5Z)-5-(2-furfurylidene)-3-(3-pyridyl)-2-thioxo-thiazolidin-4-one::(5Z)-5-(furan-2-ylmethylidene)-3-pyridin-3-yl-2-sulfanylidene-1,3-thiazolidin-4-one::CHEMBL1609550::MLS001005166::SMR000378042::cid_1591868

SMILES O=C1N(C(=S)S\C1=C/c1ccco1)c1cccnc1

InChI Key InChIKey=FMAMMNRLZOOXEN-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50679   

LigandPNGBDBM50679(cid_1591868 | SMR000378042 | MLS001005166 | (5Z)-5...)
Affinity DataIC50: 3.16E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetGlycoprotein 42(HHV-4)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM50679(cid_1591868 | SMR000378042 | MLS001005166 | (5Z)-5...)
Affinity DataIC50: 5.00E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Theodore Jardetzky; Northw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50679(cid_1591868 | SMR000378042 | MLS001005166 | (5Z)-5...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetAlbumin(Bovine)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50679(cid_1591868 | SMR000378042 | MLS001005166 | (5Z)-5...)
Affinity DataIC50: 9.41E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetT cell receptor alpha variable 4(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50679(cid_1591868 | SMR000378042 | MLS001005166 | (5Z)-5...)
Affinity DataIC50: 9.41E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [1-999,I813T](Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50679(cid_1591868 | SMR000378042 | MLS001005166 | (5Z)-5...)
Affinity DataIC50: 1.22E+5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay
Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50679(cid_1591868 | SMR000378042 | MLS001005166 | (5Z)-5...)
Affinity DataIC50: 1.22E+5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay