BDBM506978 2-(3-fluorophenyl)-4-hydroxy-N- methoxy-N-methyl-1,3-thiazole-5- carboxamide::US11046662, Compound 3

SMILES CON(C)C(=O)c1sc(nc1O)-c1cccc(F)c1

InChI Key InChIKey=HNWOSUNGXMCOFL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 506978   

LigandPNGBDBM506978(2-(3-fluorophenyl)-4-hydroxy-N- methoxy-N-methyl-1...)
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

LigandPNGBDBM506978(2-(3-fluorophenyl)-4-hydroxy-N- methoxy-N-methyl-1...)
Affinity DataIC50: 96nMAssay Description:Inhibition of human TRPM8 expressed in HEK293 cells assessed as reduction in ethyl 4-methoxy-2-phenylthiazole-5-carboxylate induced Ca2+ efflux prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed