BDBM50725 2-Chloro-5-{5-[(naphtho[2,1-b]furan-2-carbonyl)-hydrazonomethyl]-furan-2-yl}-benzoic acid::5-[5-[(benzo[e][1]benzofuran-2-carbonylhydrazinylidene)methyl]furan-2-yl]-2-chlorobenzoic acid::5-[5-[(benzo[e][1]benzofuran-2-ylcarbonylhydrazinylidene)methyl]furan-2-yl]-2-chloranyl-benzoic acid::5-[5-[(benzo[e]benzofuran-2-carbonylhydrazono)methyl]-2-furyl]-2-chloro-benzoic acid::5-[5-[[[2-benzo[e]benzofuranyl(oxo)methyl]hydrazinylidene]methyl]-2-furanyl]-2-chlorobenzoic acid::MLS001043284::SMR000415050::cid_1931770

SMILES OC(=O)c1cc(ccc1Cl)-c1ccc(C=NNC(=O)c2cc3c(ccc4ccccc34)o2)o1

InChI Key InChIKey=FLKOSYUFXVTPTM-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50725   

LigandPNGBDBM50725(5-[5-[(benzo[e][1]benzofuran-2-carbonylhydrazinyli...)
Affinity DataIC50: 1.55E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetM1 family aminopeptidase(Plasmodium falciparum (isolate FcB1 / Columbia))
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM50725(5-[5-[(benzo[e][1]benzofuran-2-carbonylhydrazinyli...)
Affinity DataIC50: 9.45E+3nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2011
Entry Details
PCBioAssay
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50725(5-[5-[(benzo[e][1]benzofuran-2-carbonylhydrazinyli...)
Affinity DataEC50:  1.50E+5nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2011
Entry Details
PCBioAssay
TargetGlycogen synthase kinase-3 beta(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50725(5-[5-[(benzo[e][1]benzofuran-2-carbonylhydrazinyli...)
Affinity DataEC50: >3.00E+5nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay