BDBM508295 1-(2-chlorophenyl)-7-cyclopropyl-4- ((2-methoxyethyl)amino)quinazolin- 2(1H)-one::US11046691, Compound 606

SMILES COCCNc1nc(=O)n(-c2ccccc2Cl)c2cc(ccc12)C1CC1

InChI Key InChIKey=SAIKNVSKLNKRDM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 508295   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Ideaya Biosciences

US Patent
LigandPNGBDBM508295(US11046691, Compound 606 | 1-(2-chlorophenyl)-7-cy...)
Affinity DataIC50: 200nMAssay Description:MAT2A enzyme is incubated with a test compound in DMSO or DMSO and its substrates (L-methionine and ATP) in a microtiter plate. The enzymatic reactio...More data for this Ligand-Target Pair
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Date in BDB:
12/27/2021
Entry Details
US Patent