BDBM508583 (R)-2-(4-(1-(2,3-dihydrobenzorbiri,41dioxin-6-yl)ethyl)piperazin-1-yl)-N,N-dimethylthiazole-5-carboxamide and (S)-2-(4-(1-(2,3-dihydrobenzorbin,41dioxin-6-yl)ethyl)piperazin-1-yl)-N,N-dimethylthiazole-5-carboxamide::US11046712, No 63::US11046712, No 64

SMILES C[C@H](N1CCN(CC1)c1ncc(s1)C(=O)N(C)C)c1ccc2OCCOc2c1

InChI Key InChIKey=ZCHMXUXNRFQNKH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 508583   

TargetProtein O-GlcNAcase(Human)
Asceneuron

US Patent
LigandPNGBDBM508583((R)-2-(4-(1-(2,3-dihydrobenzorbiri,41dioxin-6-yl)e...)
Affinity DataIC50: 50nMAssay Description:5 μI of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Asceneuron

US Patent
LigandPNGBDBM508583((R)-2-(4-(1-(2,3-dihydrobenzorbiri,41dioxin-6-yl)e...)
Affinity DataIC50: 5.50E+3nMAssay Description:5 μI of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
US Patent