BDBM509137 Compound 1-47::US11072585, Example 36

SMILES NCc1cc(O[C@H]2CCCN(C2)C(=O)Cc2ccc(Cl)c(Cl)c2)nc(c1)C(F)(F)F

InChI Key InChIKey=RAVIQFQJZMTUBX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 509137   

TargetLysyl oxidase homolog 2(Human)
Pharmakea

US Patent
LigandPNGBDBM509137(US11072585, Example 36 | Compound 1-47)
Affinity DataIC50: 300nMAssay Description:LOXL2 amine oxidase activity is evaluated by measuring Amplex Red fluorescence using 10-20× concentrated conditioned media from CHO cells stably expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2022
Entry Details
US Patent