BDBM509166 BDBM509179::Compound 1-201::US11072585, Example 63

SMILES NCc1cc(Oc2cccc(c2)C(=O)NCC2(O)CCC2)nc(c1)C(F)(F)F

InChI Key InChIKey=XBCVWRJFZFHAKX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 509166   

TargetLysyl oxidase homolog 2(Human)
Pharmakea

US Patent
LigandPNGBDBM509166(BDBM509179 | Compound 1-201 | US11072585, Example ...)
Affinity DataIC50: 300nMAssay Description:LOXL2 amine oxidase activity is evaluated by measuring Amplex Red fluorescence using 10-20× concentrated conditioned media from CHO cells stably expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2022
Entry Details
US Patent

TargetLysyl oxidase homolog 2(Human)
Pharmakea

US Patent
LigandPNGBDBM509166(BDBM509179 | Compound 1-201 | US11072585, Example ...)
Affinity DataIC50: 300nMAssay Description:LOXL2 amine oxidase activity is evaluated by measuring Amplex Red fluorescence using 10-20× concentrated conditioned media from CHO cells stably expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2022
Entry Details
US Patent