BDBM509216 Compound 1-134::US11072585, Example 111

SMILES Cc1cc(=O)n(Cc2cc(CN)cc(n2)C(F)(F)F)c(=O)n1Cc1ccccc1

InChI Key InChIKey=CXYQWBDIFFPVDM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 509216   

TargetLysyl oxidase homolog 2(Human)
Pharmakea

US Patent
LigandPNGBDBM509216(US11072585, Example 111 | Compound 1-134)
Affinity DataIC50: 300nMAssay Description:LOXL2 amine oxidase activity is evaluated by measuring Amplex Red fluorescence using 10-20× concentrated conditioned media from CHO cells stably expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2022
Entry Details
US Patent