BDBM510475 (5S,8S)-N- (2,4-dichloro- 6-fluorobenzyl)- 5-fluoro- 8-methoxy-5,6,7,8- tetrahydroquinoline- 5-carboxamide::US11077100, Example 335

SMILES CO[C@H]1CC[C@@](F)(C(=O)NCc2c(F)cc(Cl)cc2Cl)c2cccnc12

InChI Key InChIKey=DMRIBHMCBPRAIW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 510475   

TargetP2X purinoceptor 7(Human)
Raqualia Pharma

US Patent
LigandPNGBDBM510475((5S,8S)-N- (2,4-dichloro- 6-fluorobenzyl)- 5-fluor...)
Affinity DataIC50: 50nMAssay Description:1. Wash each well with 80 microL of assay buffer (20 mM HEPES, 1×HBSS, pH 7.4 adjusted with NaOH) three times and leave 20 microL using plate washer,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent