BDBM510758 US11078188, Example 39

SMILES C[C@H]1CN(C[C@@H](C)N1)C(=O)c1nc(-c2ccc3N(C)C(=O)C(C)N(C4CCOCC4)c3c2)n(n1)-c1ccc(C)cc1

InChI Key InChIKey=NDXPEBDMEQBNIT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 510758   

TargetBromodomain-containing protein 4(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM510758(US11078188, Example 39)
Affinity DataIC50: 13.6nMAssay Description:Expression and purification of the BRD4(I) recognition domain: colonies of newly transformed plasmid DNA from E. coli BL21(DE3)-condon plus-RIL cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
Go to US Patent