BDBM510825 US11078197, Example 2

SMILES CC(C)(O)CCc1ccc2c(cnn2c1C1CC1)C(=O)N[C@H]1C[C@@]2(C1)CC(C2)Oc1c(sc2ccccc12)C(N)=O

InChI Key InChIKey=YANLHVGCCLGQIT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 510825   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM510825(US11078197, Example 2)
Affinity DataIC50: 2.00E+4nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent