BDBM510995 5-(4- Aminoimidazo[2,1- f][1,2,4]triazin-7- yl)-2-(1- phenylethyl) isoindolin-1-one::US11078204, Ex. No. 12

SMILES CC(N1Cc2cc(ccc2C1=O)-c1cnc2c(N)ncnn12)c1ccccc1

InChI Key InChIKey=NWVWXHDWXUZVBY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 510995   

LigandPNGBDBM510995(5-(4- Aminoimidazo[2,1- f][1,2,4]triazin-7- yl)-2-...)
Affinity DataIC50: 100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 L. Inhibi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent

LigandPNGBDBM510995(5-(4- Aminoimidazo[2,1- f][1,2,4]triazin-7- yl)-2-...)
Affinity DataIC50: 500nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 L. Inhibi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent