BDBM5110 3-nitro-N-[(2Z)-3,4,5-trimethyl-2,3-dihydro-1,3-thiazol-2-ylidene]benzene-1-sulfonamide::N-(3,4,5-Trimethyl-1,3-thiazol-2(3H)-ylidene)-3-nitrobenzenesulfonamide::thiazolidenebenzenesulfonamide deriv. 17c

SMILES Cc1s\c(=N/S(=O)(=O)c2cccc(c2)[N+]([O-])=O)n(C)c1C

InChI Key InChIKey=STPYCDICWGOWHP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 5110   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical

LigandPNGBDBM5110(3-nitro-N-[(2Z)-3,4,5-trimethyl-2,3-dihydro-1,3-th...)
Affinity DataIC50: 970nMpH: 8.4 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical

LigandPNGBDBM5110(3-nitro-N-[(2Z)-3,4,5-trimethyl-2,3-dihydro-1,3-th...)
Affinity DataIC50: 3.30E+4nMpH: 8.4 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical

LigandPNGBDBM5110(3-nitro-N-[(2Z)-3,4,5-trimethyl-2,3-dihydro-1,3-th...)
Affinity DataIC50: 5.00E+4nMpH: 8.4 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2005
Entry Details Article
PubMed