BDBM511019 8-Amino-3-(2-((S)-1-cyclopropylethyl)- 1-oxoisoindolin-5-yl)-N-(3- hydroxytetrahydro-2H-pyran-4- yl)imidazo[1,2-a]pyrazine-6- carboxamide, trifluoroacetate salt (mixture of two diastereomers, each of which is trails relative stereochemistry at::US11078204, Ex. No. 32

SMILES C[C@@H](C1CC1)N1Cc2cc(ccc2C1=O)-c1cnc2c(N)nc(cn12)C(=O)NC1CCOCC1O

InChI Key InChIKey=OEGOVYLGFHBWHN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 511019   

LigandPNGBDBM511019(8-Amino-3-(2-((S)-1-cyclopropylethyl)- 1-oxoisoind...)
Affinity DataIC50: 100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 L. Inhibi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent

LigandPNGBDBM511019(8-Amino-3-(2-((S)-1-cyclopropylethyl)- 1-oxoisoind...)
Affinity DataIC50: 2.00E+3nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 L. Inhibi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent