BDBM511021 (S)-5-(8-Amino-6-(2- methylthiazol-5- yl)imidazo[1,2-a]pyrazin- 3-yl)-2-(1- cyclopropylethyl)-7- (methylsulfonyl)isoindolin- 1-one, trifluoroacetate salt (single enantiomer::US11078204, Ex. No. 34

SMILES C[C@@H](C1CC1)N1Cc2cc(cc(c2C1=O)S(C)(=O)=O)-c1cnc2c(N)nc(cn12)-c1cnc(C)s1

InChI Key InChIKey=PAEMTSOVQJQCCK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 511021   

LigandPNGBDBM511021((S)-5-(8-Amino-6-(2- methylthiazol-5- yl)imidazo[1...)
Affinity DataIC50: 100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 L. Inhibi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent

LigandPNGBDBM511021((S)-5-(8-Amino-6-(2- methylthiazol-5- yl)imidazo[1...)
Affinity DataIC50: 100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 L. Inhibi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent