BDBM511169 2-benzyl-2-(((2R,3S,4R,5R)-5-(2-chloro-6-((cyclopropylmethyl)amino)-9H-purin-9-yl)-3-ethynyl-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)malonic acid::US11078228, Example 92

SMILES O[C@H]1[C@@H](O[C@H](COC(Cc2ccccc2)C(O)=O)[C@]1(O)C#C)n1cnc2c(NCC3CC3)nc(Cl)nc12

InChI Key InChIKey=RLMUJLGZTBZDBZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 511169   

Target5'-nucleotidase(Human)
Calithera Biosciences

US Patent
LigandPNGBDBM511169(2-benzyl-2-(((2R,3S,4R,5R)-5-(2-chloro-6-((cyclopr...)
Affinity DataIC50: 0.800nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent