BDBM512389 Preparation of 4-(3-((2,6-dimethylphenyl)amino)-6-((1,2,3,4-tetrahydroisoquinoline-7-yl)amino)-1H-pyrazolo[3,4-d]pyrimidine-1-yl)cyclohexane-1-ol::US11084824, Example 54

SMILES Cc1cccc(C)c1Nc1nn(C2CCC(O)CC2)c2nc(Nc3ccc4CCNCc4c3)ncc12

InChI Key InChIKey=ZFOFWOGXZQNDBB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 512389   

TargetTyrosine-protein kinase BTK(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM512389(Preparation of 4-(3-((2,6-dimethylphenyl)amino)-6-...)
Affinity DataIC50: 1.14nMAssay Description:BTK enzyme evaluation with each compound of examples of the invention was performed by using BTK enzyme inhibition diagnosis kit (Cisbio, Codolet, Fr...More data for this Ligand-Target Pair
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Date in BDB:
1/24/2022
Entry Details
US Patent