BDBM512828 acs.jmedchem.1c00409_ST.423

SMILES Cn1c2nc3n(CC#Cc4ccc(Cl)c(Cl)c4)ccn3c2c(=O)n(C)c1=O

InChI Key InChIKey=VYUGMEGJNIINBO-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 512828   

TargetReplicase polyprotein 1ab(2019-nCoV)
Michigan State University

LigandPNGBDBM512828(acs.jmedchem.1c00409_ST.423)
Affinity DataIC50: 2.25E+4nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2022
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Michigan State University

LigandPNGBDBM512828(acs.jmedchem.1c00409_ST.423)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of recombinant SARS-CoV-2 main protease expressed in Escherichia coli BL21 using Dabcyl-EDANS and Boc-Abu-Tle-Leu-Gln-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Michigan State University

LigandPNGBDBM512828(acs.jmedchem.1c00409_ST.423)
Affinity DataKi:  1.11E+4nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2022
Entry Details Article
PubMed