BDBM513334 US11091471, Example RE-B::US20240279218, Example RE-B

SMILES Cc1onc(c1COc1ccc(nn1)C(=O)NC1CCOCC1)-c1ccc(Cl)cn1

InChI Key InChIKey=TXIWNLQFRATZFL-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 513334   

TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM513334(US11091471, Example RE-B | US20240279218, Example ...)
Affinity DataKi:  0.400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetIntegrin alpha-5(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM513334(US11091471, Example RE-B | US20240279218, Example ...)
Affinity DataKi:  0.400nMAssay Description:Electrophysiological experiments were performed on days 3 to 5 after the micro-injection of mRNA. During the experiment the oocytes were constantly s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2022
Entry Details
US Patent

LigandPNGBDBM513334(US11091471, Example RE-B | US20240279218, Example ...)
Affinity DataKi:  1.10nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandPNGBDBM513334(US11091471, Example RE-B | US20240279218, Example ...)
Affinity DataKi:  1.90nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2025
Entry Details
US Patent

LigandPNGBDBM513334(US11091471, Example RE-B | US20240279218, Example ...)
Affinity DataKi:  3.40nMAssay Description:Table 1 and 3: Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]Fluma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2025
Entry Details
US Patent

LigandPNGBDBM513334(US11091471, Example RE-B | US20240279218, Example ...)
Affinity DataKi:  18.4nMAssay Description:Table 1 and 3: Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]Fluma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2025
Entry Details
US Patent