BDBM513930 US11059818, Example 55

SMILES NC1CCC(C1)Oc1cccc(Cn2cc(cn2)C(CCO)c2cc(N)nc3[nH]nnc23)c1

InChI Key InChIKey=QLMDSONJYOXWKD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 513930   

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM513930(US11059818, Example 55)
Affinity DataIC50: 550nMAssay Description:MPO peroxidation activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Amplex Red (Invitrogen Cat. #A12222) which can...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent

TargetMyeloperoxidase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM513930(US11059818, Example 55)
Affinity DataIC50: 550nMAssay Description:MPO chlorination activity was measured in 100 mM KPi (pH 7.4) by utilizing the non-fluorescent reagent Aminophenyl fluorescein (APF, Invitrogen Cat. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
US Patent