BDBM513945 4-(2-((8-(((1,1,1,3,3,3-Hexafluoropropan-2- yl)oxy)carbonyl)-1,8-diazaspiro[4.5]decan-1- yl)methyl)-5- (trifluoromethyl)phenoxy)cyclohexane-1- carboxylic acid::US11059822, Example 15::US11691975, Example 15

SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2ccc(cc2OC2CCC(CC2)OC=O)C(F)(F)F)CC1)C(F)(F)F

InChI Key InChIKey=PENUDEQWSNYTOS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 513945   

TargetMonoglyceride lipase(Human)
H. Lundbeck

US Patent
LigandPNGBDBM513945(4-(2-((8-(((1,1,1,3,3,3-Hexafluoropropan-2- yl)oxy...)
Affinity DataIC50: 100nMAssay Description:Proteomes (human prefrontal cortex or cell membrane fractions) (50 μL, 1.0-2.0 mg/mL total protein concentration) were preincubated with varying...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2022
Entry Details
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TargetMonoglyceride lipase(Human)
H. Lundbeck

US Patent
LigandPNGBDBM513945(4-(2-((8-(((1,1,1,3,3,3-Hexafluoropropan-2- yl)oxy...)
Affinity DataIC50: 5.50E+3nMAssay Description:Proteomes (human prefrontal cortex or cell membrane fractions) (50 μL, 1.0-2.0 mg/mL total protein concentration) were preincubated with varying...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2023
Entry Details
Go to US Patent